Description
Tesamorelin is a synthetic 44–amino-acid polypeptide modeled on growth hormone–releasing hormone (GHRH), incorporating N-terminal and C-terminal modifications to enhance stability and resistance to enzymatic degradation. It binds to GHRH receptors in the anterior pituitary, promoting growth hormone (GH) secretion and subsequent stimulation of insulin-like growth factor-1 (IGF-1).
Through this pathway, Tesamorelin has been investigated for its potential effects on fat metabolism, lipodystrophy, cognitive parameters, and muscle composition in controlled research settings.


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