Description
GHRP-2 (pralmorelin) is a synthetic pentapeptide and growth hormone-releasing peptide (GHRP) that acts as an agonist of the ghrelin (growth hormone secretagogue) receptor, GHS-R1a. Although structurally related to met-enkephalin, GHRP-2 lacks neurotransmitter-like effects and instead engages endocrine pathways to stimulate growth hormone (GH) secretion. Beyond the pituitary, GHS-Rs are distributed in the hypothalamus and peripheral tissues, linking GHRP-2 to research on appetite, metabolism, inflammation, and tissue protection.


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